Mission

The mission of the Center for Insoluble Protein Structures (inSPIN) is to develop and apply new methods for analysis of proteins in insoluble biological structures, including membrane proteins, fibrillating proteins, and extracellular matrix proteins. These proteins consitute about half the proteome of any cell and are involved in essentially biological functions.

The inSPIN research center was established in 2005 by a donation from the Danish National Research Foundation. The research center combines the expertise from research groups specializing in solid- and liquid-state NMR spectroscopy, organic chemistry, protein chemistry, and biophysics. In 2010, the grant from the Danish National Research Foundation was extended by 5 years, with new the new focus to use the structural and functional insight towards biological intervention

The Center is directed by Prof. Niels Chr. Nielsen from the Interdisciplinary Nanoscience Center and Department of Chemistry at the University of Aarhus. Groupleaders are Prof. Troels Skrydstrup (Department of Chemistry), Prof. Jan J. Enghild (Department of Molecular Biology), and Prof. Daniel Otzen (Interdisciplinary Nanoscience Center).